Promethease dna reddit Members Online BRCA 2 mutation - 23&Me Raw Data - rs397507789(-;AAAAG) While I understand that you can upload the 23andMe info to Promethease, I heard that a Promethease report based on Ancestry raw data contains more than twice as many genotypes as 23andMe. But you can't test at Promethease, you can only upload your raw DNA data there, and they will accept uploads from pretty much any testing company. I followed some online instructions about narrowing down the search fields according to 'magnitude' You could try promethease, which basically just cross references your data against SNPedia for health related associations. There are some controversies Learn everything you need to know about Promethease and how you can use this low cost tool to analyze your raw DNA data and learn more about your genes. The SNPs that are reported in ancestry tests are typically selected because they do the best job of determining ancestry, not because they do the best job of identifying health issues. that's how some intersex people discover they're not XX female. Hello! I potentially foolishly submitted my DNA from Ancestry. My mom and dad both put their Ancestry DNA through Promethease, both came back no BRCA2 mutations. If you are looking for a service that covers all the health related SNPs, either you are going to spend a thousandish US dollars for a full genome or you could get Helix's exome plus. So I downloaded my raw data from myheritage and uploaded it to promethease and found that I'm a carrier of this gene : rs4307059 (T;T) (magnitude : 3 ) The promethease report seems to be legitimate, found out I may develop type 2 diabetes,prostate cancer,baldness. Best regards. I had started a process where I was Thanks. But it sometimes turns up interesting things. I'd consult a real Hi. They have a father's day sale going right offering 30x whole genome sequencing for $299 and I'm really tempted. Or check it out in the app stores TOPICS. Basically, any organization that collects DNA information is required to store it for 10 years by federal law (or something like that). Promethease reports cost $12. And I'm confused if I have the dreaded ApoE variant or not. If you are that type and prefer to have a company provide a health summary then you'll be better served by 23sndme. I would recommend doing promethease if you have a full genome sample, as it offers by far the best bang for your buck. After processing my DNA, I have figured out that our HLA-B27 genes were triggered during Desert Storm. Can your DNA be sequenced Note: I'm a geneticist, owner of DNA analysis platform biocodify. A place for discussing SNPedia, a curated wiki about human DNA variants and the source for Promethease reports. 8K subscribers in the promethease community. Additionally I had a ton of weird variants of fairly high magnitude reported on promethease where in the nebula explorer it showed no data for those SNPs or no variant in some cases. Promethease suggests paying attention and possibly reaching out to a medical professional. Myheritage bought them, and I still haven't gotten it to work! This weekend, I'm going to try and uninstal everything and follow these steps. I also notice a lot more "likely miscalls" in my Ancestry kit than I do with 23andMe. com - Free which is more than I've seen any other site do. Ancestry's DNA sample is slightly bigger than 23andMe's. I used 23andme to sequence my DNA which covers 600,000 SNPs. It still tells you the DNA you have that brings risks that aren't associated with your biological sex. codegen. If you decide to create the account they reserve the rights to share your data with their partners. No links worked and I could not update the files. This last one is 11 usd but it was helpful for me, anyways it's kinda difficult to sort/understand the results. For each of these SNPs, the Promethease curated report will tell you if you have the common or the risk variant. I'd go with the promethease report. RS10974944 mom is ill. It could possibly be that Promethease detected two X chromosomes, however, this is simply my theory. A place for discussing Promethease, a report about your DNA based on the scientific literature cited (I don’t know how attaching screenshots in Reddit works, but I can’t figure it out) and when I tried copying and pasting the text, View community ranking In the Top 10% of largest communities on Reddit. 8. Promethease is very comprehensive but it's not the most user friendly. Gotten a Promethease doesn’t offer a DNA test; you can only use a preexisting DNA file to access their features. View community ranking In the Top 10% of largest communities on Reddit. r/promethease: A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. I recently ran my raw DNA through Promethease and it has flagged two SNPs associated with vascular EDS (Ethlers-Danlos Syndrome Type 4). The best genetic test for medical purposes depends on your situation: Promethease If you choose not to create an account. Or check it out in the app It instead can tell what biological sex you are. com users. I will need to research directly on 23andme and update my post with all the Genotypes I actually have for each gene. Members Online DNA Methylation Dysfunction & Autoimmune Disorders Promethease is slightly more reliable, but there’s a fee yet there is virtually no customer service to show for it. It's isn't the most pretty or user friendly but it does a reasonable job for the price. So Promethease (or really Ancestry since P just reads the data Ancestry interprets) caught my BRCA2 mutation, but not my mom's. I have since found 5 other veterans through the US, Australia and Europe that have the exact same symptoms, DNA profile (HLA-B27 neg with #TNFRSF1A mutations) and received the anthrax vaccine. com. We analyze your raw data to generate over a thousand genetic predispositions. I wish to make analyze my DNA for (rare diseases), with Nebula Genomics (WGS 100x). For rs4420638 I have the A;G variant, which Promethease tell's me give me a 3x chance of developing Alzheimer's. eu - a free promethease-ish service for ancestry testing raw data. Members Online Promethease Processing Delay Promethease - $12 MyHeritage DNA - FREE (WTF, really? Cannot be!) GEDmatch — FREE (DNA Romance - Think that is quite the troll LOL) Sequencing. I just re-ran my same DNA file to get updated reports. 26 votes, 11 comments. A subreddit for Etsy sellers on Reddit to collaborate and discuss techniques and experiences selling their products and building their stores. Or check it out in the app stores. DNA sequencing . They said you can but they don't accept really large files and real raw DNA files are at least around 800mb or more. I used ancestry for my dna test, my mum used ancestry and father used 23andme so I have a pretty good idea of my genes. I put my Ancestry DNA results into Promethease. Members Online Ashki Male with BRCA2 Just to clarify: With a X30 or better sequence, the issue is most services don't list variants matching the reference, which are rarely harmful, in their processed VCF results; with Nebula Explore/0. Reply reply Top 8% Rank by size You could try promethease, which basically just cross references your data against SNPedia for health related associations. Promethease was located in USA, and the FDA warned them to stop their business if they were not able to stop offering pharma-products report. Anyone have experience using them or a Ancestry is much less expensive for more SNPs so overall better for Promethease specifically. you can just look at the raw data and see if there is a y chromosome to confirm. Promethease In her Promethease (that I looked after the dr pointed it out) it’s marked as red and says she has 2-4x chances of You'd have to edit your DNA with a CRISPR sequence to change it. Schizophrenia is found as a part of the standard curated Promethease report in medical conditions. Please let me know if you need more assistance with this or something else. Both Genie and Prom correctly picked up my carrier status for a common recessive condition, but both missed the second (rarer) disease for which I’m also a I recently submitted my Ancestry DNA to Promethease, having previously submitted 23andme data a few years ago, and my results this time show mutations for BRCA 1 and 2 plus Lynch syndrome (high risk of early onset colorectal cancer), although it states that these are possible miscalls as they are found in higher frequency in Ancestry. Last september MyHeritage bought Promethease and transferred the Promethease's DNA files to their database and offer "free" DNA matching, only for non-europeans. g. Just got Promethease report. Promethease is only $12 but it's a one-time cost and you can keep running reports every so often as the science advances. Any site that allows file uploads might include a feature for law enforcement to search for matches. Get app Get the Reddit app Log In Log in to Reddit. Keep in mind that most "genetic testing" companies like 23andme, Family Tree DNA, Ancestry or others use SNP chips, that only take a tiny percentage of all the DNA you have and characterize certain spots in in. eu/. The information you get is "4th percentile of male pattern baldness," "92nd percentile for risk tolerance," "34th percentile for weight," etc. eu is a decent free alternative to Promethease that gives you much of the same information. org is free and it has some reports like promethease. I've been looking through my genes and the following are those I have that are associated with Autism. Or check it out in the app stores A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. It doesn't save your file like Promethease does. Luckily promethease let you upload a raw DNA file. Posted by u/stfarrow - 1 vote and 2 comments A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. Does that mean I have the bad ApoE e4 variant? I also have rs5882(G;G), which is associated with a 70% lower risk of Alzheimer's. For those who don't know, Promethease is a website where you can upload your raw data from 23AndMe, MyHeritage and other Human DNA analyzing programs; it will itself analyze the raw data and give you genetic and health infos (predisposition to certain diseases, phenotype, etc) basing the results on the info gathered in a big ass database. 23andMe’s health DNA test is priced at $199. Log In / Sign Up; Advertise on Reddit; Shop Collectible Avatars; Get the Reddit app Scan this QR code to download the app now. Open comment sort options If you mention this reddit post or DM me you'll get a 70-80% discount. SNPedia only had 43 Genotypes listed for SYNGAP1 gene. If you mention this reddit post or DM me you'll get a 70-80% discount. It was confirmation of a adult-onset disease inherited recessively that we’ve never seen in our family. A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. I've seen a slight difference between 23andMe and Ancestry on Promethease (I've uploaded both of mine), with mostly overlap. Discrepancy in stated kidney disease risk Go to promethease r/promethease • by Puzzleheaded-Ad-3022. . How Promethease DNA Works After uploading my dna on Promethease and Codegen, I’ve discovered plenty but I’d like to discover more. Internet Culture (Viral) Amazing A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. com, and Sequencing. Nutcracker doesn't let you upload a raw DNA file which is kinda lame so I can't use them. It isn't comprehensive. The new report (since they were bought by the Israeli company) Promethease is by far the best third-party data analysis tool, but there are many others out there to choose from. I am unaware of how exactly it does this. Valheim; Genshin A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. We don't do any ancestry analysis; Promethease is an established and reliable company, they are actually now owned by MyHeritage. can also check sry and ar genes plus there is list of conditions on the right you can scroll through. 23andMe is the next best. Promethease - $12 MyHeritage DNA - FREE (WTF, really? Cannot be!) GEDmatch — FREE (DNA Romance - Think that is quite the troll LOL) Sequencing. Promethease is a low-cost DNA analysis service that creates a report using the raw data you get from a genetic testing company. com or Promethease DNA brings the world of genomics to your fingertips. I’m Jewish/German/Scottish husband is Italian. Promethease shows that I have the high risk versions of rs10974944 and rs12343867 after I Get the Reddit app Scan this A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. These are: rs113485686(A;G) rs587779663(A;G) In both cases, there is a possible 'false positive' disclaimer indicating it could be a miscall due to the rareness of the variance in the population. I've noticed my family doesn't really "get" the promethease output because they're not willing to dig into results. It enhances Promethease in my opinion. If you mention this reddit post or DM me you'll get a 75% discount. More than half of my results are “good” but I am extremely worried because apparently my risk of cancer (lots of Schizophrenia - Promethease. If you are interested in how your genetics influence drug response you can use gene2rx. Sorry for any mistake, english is not my mother tongue. With the use of your raw data file downloaded from a DNA testing company, such as 23andMe. May 1st - wrote a letter to support, saying about my concerns about delays and absence of notifications (even about successful DNA extraction) Today, May 2nd. That is not how promethease works. We don't do any ancestry analysis; the information you get is "4th geneticgenie. For example thats how they transfer all of their data from Promethease to MyHeritage after the company acquisition. I then confirmed it with a Color Genomics test. MyHeritage, Ancestry. GEDMatch, Promethease, and other sites do not test your DNA but they do allow you to upload a file from a testing company for additional analysis, matching, etc. Expand user menu Open settings menu. The UI is slightly better. A place for discussing Promethease, a report about your DNA based on the Get app Get the Reddit app Log In Log in to Reddit. Which DNA test is best to upload to Promethease of 23andMe, Ancestry, and MyHeritage? I already uploaded FTDNA in 2018, but now I intend to upload another test and want to have as much useful information about my DNA as possible, and I've done those four tests. Promethease will report on hundreds or thousands of snp’s, FMF only reports on a limited number of snp’s for which it has a decent body of info on. simultaneous higher and lower risk for breast In 2015 I used Promethease. Internet Culture (Viral) Amazing; Animals & Pets A place for discussing Promethease, a report about your DNA based on the scientific literature cited in A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. 4X sequencing the issue is that most of the genome hasn't been sequenced at all (Their VCF file may use imputation, but I'm not sure, that would provide the data but introduce Promethease DNA test results anxiety I have just received my results from Promethease, I used the raw data from 23andme service. Members Online Hemophilia good magnitude When i uploaded my last DNA test, it went from ancestry, to promethease with out changing the zipped file. Members Online. Is there a way I can see my maternal haplogroup by uploading my results somewhere or do I need to retest? Get the Reddit app Scan this QR code to download the app now. Promethease generates pie charts that tell the user the ratio of “good”, “bad”, and “not set” DNA health results. Promethease gave quite a bit more info--the problem is you get too many hits with Promethease, and sometimes they are contradictory (e. com - Free Thanks in advance! <3 Share Sort by: Best. I was going to edit my Tellmegen file but it’s inconsistent on what things are like, scored in a way that is seen as “opposite” in promethease (where you’ll get false positives) and what things are like, straight with SNPedia and stuff. In reviewing the report for my eye color it shows rs12913832 (G;G) genotype on chromosome 15 position 28120472. And there are a lot more. WGSE noted 47 chromosomes and did show the Y chromosome and then when I loaded the data to promethease I got this genoset (gs261). Mine came up with the same variants but gave them different weights in terms of how they might affect me. Although I haven’t seen FMF reports since they did an update. Ever since 23andme stopped providing detailed health-related results in 2013, Promethease was a sensible alternative. Members Online Hemophilia good magnitude I sent my DNA to https://codegen. (16 weeks after kit received by Dantelabs)- Received two emails simultaneously, saying that both kits have level D DNA extraction, and should be recollected. Members Online Stressing out about Schizophrenia after looking up my DNA results guys , I bought just the ancestry test on sale for 49 dollars on amazon on oct 18. Every time you want a print out or to read it you have to resubmit but the entire process took about five minutes. Gaming. I saw my doctor recently and he told me my fatigue isn't my thyroid and it could be chronic fatigue syndrome which deflated me so I haven't really been digging around in I didn’t have to do any conversations at all. Sent it on oct 19 and my results are in. I found this email on an old reddit thread and they responded within a few days. but I am not seeing a lot of Reddit posts about people using Nebula. Is that true? So I guess it comes down to whether the extra cost of 23andMe health info on top of Promethease is worth it vs. just uploading raw data from Promethease - $12 MyHeritage DNA - FREE (WTF, really? Cannot be!) GEDmatch — FREE (DNA Romance - Think that is quite the troll LOL) Sequencing. com, which provides prescription guidance from the FDA based on your data from Ancestry. Members Online DNA results help medication approvals from insurance providers? Haplotype 46/1 which increases the risk of MPNs have 4 SNPs that apparantly come together rs3780367, rs10974944, rs12343867, and rs1159782. Many have said they never got responses, but they resolved my issue. Get the Reddit app Scan this QR code to download the app now. We don't do any ancestry analysis; the information you get is "4th I've done an Ancestry dna test and uploaded it to MyHeritage, MyTrueAncestry, Promethease, GedMatch and to MyFTDNA. Promethease. Somehow, it determined that I was biologically female. It sucks. I had uploaded it elsewhere in at least one additional database. You could theoretically just upload an mtDNA or Y-DNA kit in BAM or VCF but you won't get that much information as those chromosomes don't encode very many medically relevant details. Members Online problem with uploading two tests. My dad has all three of them so I felt a little shocked by its accuracy. I can see my ancestry Promethease is slightly more reliable, but there’s a fee yet there is virtually no customer service to show for it. They will match any format against a bunch of different databases and produce a report that should be much more complete than promethease considering the price. A place for discussing Promethease, a report about your DNA based on the scientific literature cited in Get the Reddit app Scan this QR code to download the app now. Be aware the Nebula results use the later hg38 reference model commonly used for medical purposes while the autosomal/relative finding tests use the hg19 reference model, so you'll want your hg38 reference results translated into the hg19 reference. promethease can only tell you about genos that are in your raw data. 1K subscribers in the promethease community. They used to charge $5 (now up to $12, but that’s still a steal) and they Today I’m showing you how to make the most out of your Promethease report, by giving you suggestions on how to filter and sort it to produce the easiest, most digestible report. However, my raw dna data from Ancestry DNA for rs12913832 is (A;G) on chromosome 15 and position 28365618. But i don't understand if Promethease will read my VCF or BAM file? And if not, what service to choose? I'm very confused, even after hours of reading on internet. com, Promethease DNA analyzes it against genetic information collected by research institutions worldwide. FMF gives more discussion, Promethease gives topical highlights and links to studies, etc. Users can also filter The following are my results from Promethease. It contains information on thousands of SNPs, but you can filter it to find the ones that Keep in mind that "more SNPs" does not equate to "better health information". Members Online Peutz-Jeghers - rs137853077 (C;T) Get the Reddit app Scan this QR code to download the app now. Livewello - 20 dollars for for various reports generated from ancestry raw data files. I'm also going to include markers associated with ADHD as I'm interested in learning about the links between them. Members Online I had multiple JAK2 findings and my most recent labwork indicates high RBC This is the right answer. com - Free If you mention this reddit post or DM me you'll get a 70-80% discount. Don't understand why no other service does. Also its an Isreali company with in itself is kinda sketchy. Members Online Promethease Processing Delay You can use PolyCypher to analyze your raw DNA data. I had to setup a server farm for the department in charge of record retention, which involved reading through the federal laws related to storing DNA info. Both Genie and Prom correctly picked up my carrier status for a common recessive condition, but both missed the second (rarer) disease for which I’m also a I used to work for a medical research company in IT. I just found out that the promethease report only covers around 25,000 of the SNPs from 23andme. 23andMe usually covers this location, Hello, I uploaded a raw data file (the SNP VCF file not the BAM) from dante labs to promethease and the first item in the report was GS261: This is most often seen when the user mixed multiple (male and female) people into a single report. com onto Promethease and have returned a worrying result. This reports is made based on data from SNPedia, which contains ~200 SNPs tagged with schizophrenia. i might be able to give more insight if i had more of your symptoms When running dna of yours or family member through promethease? I found out something horrible I am not sure I can put on here for fear it will be found. However, my mom tested positive for the mutation via Color Genomics. Mostly the genealogy companies use SNPs with a relevance to genealogy and not so much towards helth issues (of those mentioned only A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia.
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